Dexamethasone Sodium Phosphate

Preferred Label : Dexamethasone Sodium Phosphate;

NCIt synonyms : Dexamethasone Sodium Phosphates;

NCIt related terms : Corson;

NCIt definition : A sodium phosphate salt form of Dexamethasone, a synthetic adrenal corticosteroid with potent anti-inflammatory properties. In addition to binding to specific nuclear steroid receptors, dexamethasone also interferes with NF-kB activation and apoptotic pathways. This agent lacks the salt-retaining properties of other related adrenal hormones. (NCI04);

UNII : AI9376Y64P;

InChIKey : PLCQGRYPOISRTQ-FCJDYXGNSA-L;

CAS number : 2392-39-4; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2392-39-4 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Solurex; Dalalone; Dexacen; Decaject; Dezone; Dexasone; Dekasol LA; Soludecadron; Cebedex; Corson; ReadySharp Dexamethasone; Topidex;

Chemical formula : C22H28FO8P.2Na;

ChEBI ID : CHEBI:4462;

Codes from synonyms : NSC0034521;

Details

Origin ID

C1362;

UMLS CUI

C0113286;

Automatic exact mappings (from CISMeF team)
- decapitation [MeSH Descriptor]
- dental debonding [MeSH Descriptor]
- dexamethasone 21-phosphate [Substance BNPC]
- dexamethasone 21-phosphate [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_free_acid_or_base_form
- Dexamethasone Phosphate [NCIt concept]
has_target
- Glucocorticoid Receptor [NCIt concept]
is_component_of_chemotherapy_regimen
- BDR Regimen [NCIt concept]
- Bortezomib/Dexamethasone/Venetoclax Regimen [NCIt concept]
- CCD Regimen [NCIt concept]
- CaRD Regimen [NCIt concept]
- Cyclophosphamide/Dexamethasone/Rituximab Regimen [NCIt concept]
- DCEP/Bortezomib Regimen [NCIt concept]
- Dara-Pd Regimen [NCIt concept]
- Daratumumab and Hyaluronidase/Dexamethasone/Pomalidomide Regimen [NCIt concept]
- Dexamethasone/Elotuzumab/Pomalidomide Regimen [NCIt concept]
- Dexamethasone/Isatuximab/Pomalidomide Regimen [NCIt concept]
- Dexamethasone/Liposomal Doxorubicin/Etoposide/Ibrutinib/Rituximab/Temozolomide Regimen [NCIt concept]
- Dexamethasone/Liposomal Doxorubicin/Etoposide/Rituximab/Temozolomide Regimen [NCIt concept]
- Dexamethasone/Selinexor Regimen [NCIt concept]
- R-DHA Regimen [NCIt concept]
- VTD Regimen [NCIt concept]
is_salt_form_of
- Dexamethasone Phosphate [NCIt concept]

Keyword's position in hierarchy(ies) :

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