Prednisolone Sodium Metasulfobenzoate

Preferred Label : Prednisolone Sodium Metasulfobenzoate;

NCIt synonyms : Prednisolone Methylsulfobenzoate; Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-, 21-(M-sulfobenzoate), Monosodium Salt; Prednisolone Sodium 21-M-Sulfobenzoate; Prednisolone Sodium Metasulphobenzoate;

NCIt related terms : PREDNISOLONE SODIUM METAZOATE;

NCIt definition : A poorly adsorbed analog of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisolone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cells populations. (NCI);

UNII : D345THM53T;

InChIKey : RWFZSORKWFPGNE-VDYYWZOJSA-M;

CAS number : 630-67-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 630-67-1 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Corti-Clyss; Predenema; Predfoam; Predocol;

Molecule name : ATL-2502;

Chemical formula : C28H31O9S.Na;

Details

Origin ID

C1862;

UMLS CUI

C0889299;

Automatic exact mappings (from CISMeF team)
- Prednisolone metasulfobenzoate sodium (substance) [SNOMED CT concept]
See also inter- (CISMeF)
- Prednisolone methylsulfobenzoate (substance) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Prednisolone metasulfobenzoate sodium (substance) [SNOMED CT concept]
- Prednisolone methylsulfobenzoate (substance) [SNOMED CT concept]
- prednisolone 21-(3-sodium-sulphobenzoate) [Substance BNPC]
- prednisolone 21-3-sulfobenzoate [MeSH Supplementary Concept]
- prednisolone sodium metasulphobenzoate [MeSH concept]
Validated automatic mappings to NTBT
- prednisolone 21-3-sulfobenzoate [MeSH Supplementary Concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Prednisolone [NCIt concept]
is_salt_form_of
- Prednisolone [NCIt concept]

Keyword's position in hierarchy(ies) :

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