Preferred Label : Prednisolone Sodium Metasulfobenzoate;
NCIt synonyms : Prednisolone Methylsulfobenzoate; Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-, 21-(M-sulfobenzoate), Monosodium
Salt; Prednisolone Sodium 21-M-Sulfobenzoate; Prednisolone Sodium Metasulphobenzoate;
NCIt related terms : PREDNISOLONE SODIUM METAZOATE;
NCIt definition : A poorly adsorbed analog of prednisolone, a synthetic glucocorticoid with anti-inflammatory
and immunomodulating properties. After cell surface receptor attachment and cell entry,
prednisolone enters the nucleus where it binds to and activates specific nuclear receptors,
resulting in an altered gene expression and inhibition of proinflammatory cytokine
production. This agent also decreases the number of circulating lymphocytes, induces
cell differentiation, and stimulates apoptosis in sensitive tumor cells populations.
(NCI);
UNII : D345THM53T;
InChIKey : RWFZSORKWFPGNE-VDYYWZOJSA-M;
CAS number : 630-67-1;
Drug name : Corti-Clyss; Predenema; Predfoam; Predocol;
Molecule name : ATL-2502;
Chemical formula : C28H31O9S.Na;
Origin ID : C1862;
UMLS CUI : C0889299;
See also inter- (CISMeF)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to NTBT
chemical_or_drug_is_metabolized_by_enzyme
concept_is_in_subset
has_free_acid_or_base_form
is_salt_form_of