Testosterone Undecanoate

Preferred Label : Testosterone Undecanoate;

NCIt synonyms : Testosterone 17Beta-Undecylate;

NCIt definition : The undecanoate ester form of the androgen testosterone, with gonadotropin-secretory inhibiting and hormone replacement activity. As testosterone inhibits the secretion of gonadotropins from the pituitary gland, administration of testosterone decreases the secretion of luteinizing hormone (LH). By inhibiting LH secretion, the growth of Leydig cells, which are normally stimulated by LH to produce testosterone, may be suppressed. In addition, this agent promotes the maintenance of male sex characteristics and can be used for testosterone replacement in hypogonadal males.;

UNII : H16A5VCT9C;

InChIKey : UDSFVOAUHKGBEK-CNQKSJKFSA-N;

CAS number : 5949-44-0;

Drug name : Andriol; Restandol; Pantestone; Nebido;

Chemical formula : C30H48O3;

Details

Origin ID

C1249;

UMLS CUI

C0076195;

Automatic exact mappings (from CISMeF team)
- Testosterone undecanoate (product) [Inactive SNOMED CT concept]
Semantic type(s)
- Hormone [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- 17.beta.-hydroxyandrost-4-en-3-one undecanoate [Substance BNPC]
- Testosterone undecanoate (product) [Inactive SNOMED CT concept]
- Testosterone undecanoate (substance) [SNOMED CT concept]
- testosterone undecanoate [MeSH concept]
- testosterone undecanoate [MeSH Supplementary Concept]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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