NCIt definition : The pamoate salt of imipramine, a synthetic dibenzazepine derivative with anti-depressant
activity. Imipramine pamoate, a tricyclic antidepressant (TCA) potentiates the activity
of adrenergic synapses by blocking the re-uptake of norepinephrine and serotonin,
thereby preventing their degradation and increasing their availability. This drug
also has antimuscarinic and anti-histamine properties, which contribute to its side
effects.;