Imipramine Pamoate

Preferred Label : Imipramine Pamoate;

NCIt definition : The pamoate salt of imipramine, a synthetic dibenzazepine derivative with anti-depressant activity. Imipramine pamoate, a tricyclic antidepressant (TCA) potentiates the activity of adrenergic synapses by blocking the re-uptake of norepinephrine and serotonin, thereby preventing their degradation and increasing their availability. This drug also has antimuscarinic and anti-histamine properties, which contribute to its side effects.;

UNII : MC34P30298;

InChIKey : BPQZYOJIXDMZSX-UHFFFAOYSA-N;

CAS number : 10075-24-8; 22540-17-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 10075-24-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 22540-17-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Tofranil-PM;

Chemical formula : C23H16O6.2C19H24N2;

Details

Origin ID

C61788;

UMLS CUI

C0304368;

Automatic exact mappings (from CISMeF team)
- Imipramine Pamoate [MeSH concept]
Currated CISMeF NLP mapping
- Imipramine pamoate (substance) [SNOMED CT concept]
- imipramine pamoate [SNOMED Notion]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Imipramine pamoate (substance) [SNOMED CT concept]
- imipramine pamoate [SNOMED Notion]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450 2C19 [NCIt concept]
- Cytochrome P450 2D6 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
has_free_acid_or_base_form
- Imipramine [NCIt concept]
is_salt_form_of
- Imipramine [NCIt concept]

Keyword's position in hierarchy(ies) :

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