NCIt definition : A synthetic tricyclic derivative, antidepressant Imipramine enhances monoamine neurotransmission
in certain areas of the brain. It also induces sedation through histamine 1 receptor
blockage; hypotension through beta-adrenergic blockage; and diverse parasympatholytic
effects. Imipramine has less sedative effect than other members of its therapeutic
family. It is used in major depression, dysthymia, bipolar depression, attention-deficit
disorders, agoraphobia, and panic disorders. (NCI04);
UNII : OGG85SX4E4;
InChIKey : BCGWQEUPMDMJNV-UHFFFAOYSA-N;
CAS number : 50-49-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 50-49-7
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