aryl hydrocarbon hydroxylases

Preferred Label : aryl hydrocarbon hydroxylases;

MeSH definition : A large group of cytochrome P-450 (heme-thiolate) monooxygenases that complex with NAD(P)H-FLAVIN OXIDOREDUCTASE in numerous mixed-function oxidations of aromatic compounds. They catalyze hydroxylation of a broad spectrum of substrates and are important in the metabolism of steroids, drugs, and toxins such as PHENOBARBITAL, carcinogens, and insecticides.;

MeSH synonym : monooxygenases, microsomal; hydroxylases, aryl hydrocarbon; microsomal monooxygenases;

MeSH hyponym : xenobiotic monooxygenases; Monooxygenases, Xenobiotic;

MeSH Related Number : xenobiotic monooxygenases; EC 1.14.14.1;

Registry Number MeSH : EC 1.14.14.1;

Related CAS MeSH : EC 1.14.14.1 (Xenobiotic monooxygenases);

Is substance : O;

UNII : EC 1.14.14.1;

Details

Origin ID

D001189;

UMLS CUI

C0003927;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- AHRR wt Allele [NCIt concept]
- Aromatase [NCIt concept]
- CYP1A1 wt Allele [NCIt concept]
- Cytochrome P450 19A1 [NCIt concept]
- Cytochrome P450 2C18 [NCIt concept]
- Cytochrome P450 2C19 [NCIt concept]
- Cytochrome P450 2C8 [NCIt concept]
- Cytochrome P450 2C9 [NCIt concept]
- Cytochrome P450 2D6 [NCIt concept]
- Cytochrome P450 2E1 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
- Cytochrome p450, subfamily I, polypeptide 1 [OMIM gene]
- cytochrome P450 family 2 subfamily C member 19 [ORDO Gene]
Indexing information
- 3-methylsulfonyl-4,5,3',4'-tetrachlorobiphenyl [MeSH Supplementary Concept]
- 9-chloro-7H-dibenzo(ag)carbazole [MeSH Supplementary Concept]
Record concept(s)
- aryl hydrocarbon hydroxylases [MeSH concept]
- xenobiotic monooxygenases [MeSH concept]
Related MeSH Supplementary Concept(s)
- 4-chlorobiphenyl hydroxylase [MeSH Supplementary Concept]
- 7,12-dimethylbenz(a)anthracene hydroxylase [MeSH Supplementary Concept]
- CYP1A4 protein, gallus gallus [MeSH Supplementary Concept]
- CYP2A10 protein, oryctolagus cuniculus [MeSH Supplementary Concept]
- CYP2A11 protein, oryctolagus cuniculus [MeSH Supplementary Concept]
- CYP2A13 protein, human [MeSH Supplementary Concept]
- CYP2A7 protein, human [MeSH Supplementary Concept]
- CYP2A8 protein, mesocricetus auratus [MeSH Supplementary Concept]
- CYP2C11 protein, rat [MeSH Supplementary Concept]
- CYP2C18 protein, human [MeSH Supplementary Concept]
- CYP2C19 protein, human [MeSH Supplementary Concept]
- CYP2C3 protein, oryctolagus cuniculus [MeSH Supplementary Concept]
- CYP2C8 protein, human [MeSH Supplementary Concept]
- CYP2C8 protein, mouse [MeSH Supplementary Concept]
- CYP2C9 protein, human [MeSH Supplementary Concept]
- CYP2K1 protein, oncorhynchus mykiss [MeSH Supplementary Concept]
- CYP3A43 protein, human [MeSH Supplementary Concept]
- CYP3A7 protein, human [MeSH Supplementary Concept]
- CYP4F12 protein, human [MeSH Supplementary Concept]
- CYP4F8 protein, human [MeSH Supplementary Concept]
- Cyp2a1 protein, rat [MeSH Supplementary Concept]
- Cyp2a4 protein, mouse [MeSH Supplementary Concept]
- Cyp2a5 protein, mouse [MeSH Supplementary Concept]
- Cyp2b10 protein, mouse [MeSH Supplementary Concept]
- Cyp2b19 protein, mouse [MeSH Supplementary Concept]
- Cyp2b3 protein, rat [MeSH Supplementary Concept]
- Cyp2b9 protein, mouse [MeSH Supplementary Concept]
- Cyp2c40 protein, mouse [MeSH Supplementary Concept]
- Cyp2d2 protein, rat [MeSH Supplementary Concept]
- Cyp2d4 protein, rat [MeSH Supplementary Concept]
- Cyp3a62 protein, rat [MeSH Supplementary Concept]
- Cyp3a9 protein, rat [MeSH Supplementary Concept]
- Fmo-2 protein, Drosophila [MeSH Supplementary Concept]
- acetanilide hydroxylase [MeSH Supplementary Concept]
- aklavinone 11-hydroxylase [MeSH Supplementary Concept]
- biphenyl-2-hydroxylase [MeSH Supplementary Concept]
- biphenyl-3-hydroxylase [MeSH Supplementary Concept]
- biphenyl-4-hydroxylase [MeSH Supplementary Concept]
- chlorzoxazone 6-hydroxylase, rat [MeSH Supplementary Concept]
- cytochrome P-450 CYP1A3 (rainbow trout) [MeSH Supplementary Concept]
- cytochrome P-450 CYP1A5 [MeSH Supplementary Concept]
- cytochrome P-450 CYP2A16 (hamster) [MeSH Supplementary Concept]
- cytochrome P-450 CYP2B11 (dog) [MeSH Supplementary Concept]
- cytochrome P-450 CYP2B4 (rabbit) [MeSH Supplementary Concept]
- cytochrome P-450 CYP2B5 (rabbit) [MeSH Supplementary Concept]
- cytochrome P-450 CYP2D15 (dog) [MeSH Supplementary Concept]
- cytochrome P-450 CYP2D16 (guinea pig) [MeSH Supplementary Concept]
- cytochrome P-450 CYP2D19 (marmoset) [MeSH Supplementary Concept]
- cytochrome P-450 CYP2D30 (marmoset) [MeSH Supplementary Concept]
- cytochrome P-450 CYP2G1 [MeSH Supplementary Concept]
- cytochrome P-450 CYP3A14 (guinea pig) [MeSH Supplementary Concept]
- cytochrome P-450 CYP3A21 (marmoset) [MeSH Supplementary Concept]
- cytochrome P-450 CYP3A37 (chicken) [MeSH Supplementary Concept]
- cytochrome P-450 CYP3A6 (rabbit) [MeSH Supplementary Concept]
- cytochrome P-450 CYP3A65, zebrafish [MeSH Supplementary Concept]
- cytochrome P-450 CYP4A4 (rabbit) [MeSH Supplementary Concept]
- cytochrome P-450 CYP4B1 [MeSH Supplementary Concept]
- cytochrome P-450 CYP6B1 (butterfly) [MeSH Supplementary Concept]
- cytochrome P-450 CYP6B17, butterfly [MeSH Supplementary Concept]
- cytochrome P-450 CYP6B3 (butterfly) [MeSH Supplementary Concept]
- cytochrome P-450 CYP6B4, butterfly [MeSH Supplementary Concept]
- cytochrome P450 CYP3A10 (hamster) [MeSH Supplementary Concept]
- deoxysarpagine hydroxylase [MeSH Supplementary Concept]
- ecdysone 20-hydroxylase [MeSH Supplementary Concept]
- phenanthrene-9,10-epoxidase [MeSH Supplementary Concept]
- steroid 15-alpha-hydroxylase [MeSH Supplementary Concept]
- steroid 15-beta-hydroxylase [MeSH Supplementary Concept]
- steroid 16-beta-hydroxylase [MeSH Supplementary Concept]
- steroid hormone 7-alpha-hydroxylase [MeSH Supplementary Concept]
- testosterone 7-alpha-hydroxylase, hamster [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Unspecific monooxygenase (substance) [SNOMED CT concept]
- unspecific monooxygenase [SNOMED Notion]
Validated automatic mappings to BTNT
- Cytochrome P450 1A1 [NCIt concept]
- Cytochrome P450 1A2 [NCIt concept]

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