AHRR wt Allele

Preferred Label : AHRR wt Allele;

NCIt synonyms : AHHR; Aryl-Hydrocarbon Receptor Repressor wt Allele; Arylhydrocarbon Receptor Repressor Gene; KIAA1234; AHH; BHLHE77;

NCIt definition : Human AHRR wild-type allele is located in the vicinity of 5p15.33 and is approximately 167 kb in length. This allele, which encodes aryl hydrocarbon receptor repressor protein, is involved in xenobiotic metabolism and the inhibition of aryl hydrocarbon receptor-mediated transcription. A translocation t(5;8)(p15;q13) that fuses this gene with the NCOA2 gene is associated with soft tissue angiofibroma.;

NCI Metathesaurus CUI : CL1643297;

GenBank Accession Number : AB033060;

PubMed : 22337624; 27633981;

Details

Origin ID

C177420;

UMLS CUI

C5443967;

Automatic exact mappings (from CISMeF team)
- Arylhydrocarbon receptor repressor [OMIM gene]
- Cytochrome p450, subfamily I, polypeptide 1 [OMIM gene]
- aryl hydrocarbon hydroxylases [MeSH Descriptor]
OMIM relation
- Arylhydrocarbon receptor repressor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 5p15.33 [NCIt concept]
gene_plays_role_in_process
- DNA Binding [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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