Cytochrome P450 1A1

Preferred Label : Cytochrome P450 1A1;

NCIt synonyms : EC 1.14.14.1; P450-P1; P450-1A1; Cytochrome P1-450, Dioxin-Inducible; Flavoprotein-Linked Monooxygenase; Aryl Hydrocarbon Hydroxylase; CYP1A1 Product; Microsomal Monooxygenase; P450-C; CYP1A1; P450 Form 6; Cytochrome P450, Subfamily I (Aromatic Compound-Inducible), Polypeptide 1; Cytochrome P450-P1; CYPIA1; Cytochrome P450-C; Cytochrome P450 Form 6; Cytochrome-P450-1A1;

NCIt definition : Cytochrome P450 1A1 (512 aa, 58 kDa) is encoded by the human CYP1A1 gene. This protein is involved in the metabolism of fatty acids and xenobiotics.;

NCIt note : polymorphism and susceptibility to lung cancer; process: electron transport;

Details

Origin ID

C17296;

UMLS CUI

C3252639;

OMIM relation
- Cytochrome p450, subfamily I, polypeptide 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CYP1A1 protein, human [MeSH concept]
- CYP1A1 protein, human [MeSH Supplementary Concept]
Validated automatic mappings to NTBT
- aryl hydrocarbon hydroxylases [MeSH Descriptor]
- aryl hydrocarbon hydroxylases [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CYP1A1 Gene [NCIt concept]
- Cytochrome P450 Family Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Lung [NCIt concept]
- Lymphocyte [NCIt concept]
- Placenta [NCIt concept]
gene_product_has_associated_anatomy
- Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Heme Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_of
- Lung Carcinoma [NCIt concept]
gene_product_is_biomarker_type
- Risk Marker [NCIt concept]
gene_product_is_element_in_pathway
- Fatty Acid Metabolism Pathway [NCIt concept]
- Metabolism of Xenobiotics by Cytochrome P450 Pathway [NCIt concept]
- Retinol Metabolism Pathway [NCIt concept]
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
- Tryptophan Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carcinogen Metabolism [NCIt concept]
- Detoxification [NCIt concept]
- Fatty Acid Metabolism [NCIt concept]
- Hydroxylation [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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