cytochrome p-450 cyp2e1

Preferred Label : cytochrome p-450 cyp2e1;

MeSH definition : An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.;

MeSH synonym : cyp 2e1; cyp2e1; cytochrome p450 2e1; cytochrome p-450-j; n nitrosodimethylamine demethylase; 4 nitrophenol 2 hydroxylase; cytochrome p-450 iie1; cytochrome p 450 iie1; cyp iie1; n-nitrosodimethylamine demethylase; cytochrome p-450 (alc); cytochrome p 450 j; 4-nitrophenol-2-hydroxylase; dimethylnitrosamine n-demethylase; dimethylnitrosamine n demethylase; cypiie1; cytochrome P 450 CYP2E1;

Registry Number MeSH : EC 1.14.14.1; EC 1.14.13.-;

MeSH annotation : do not confuse with other cytochrome P-450 CYP's;

Is substance : O;

Details

Origin ID

D019392;

UMLS CUI

C0010763;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Cytochrome P450 2E1 [NCIt concept]
Indexing information
- 2-(allylthio)pyrazine [MeSH Supplementary Concept]
Record concept(s)
- cytochrome P-450 CYP2E1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- cytochrome P-450 2E1, mouse [MeSH Supplementary Concept]
Related MeSH term(s)
- Cytochrome P-450 CYP2E1 Inhibitors [MeSH Descriptor]
See also (suggested by CISMeF)
- Cytochrome P-450 CYP2E1 Inducers [MeSH Descriptor]
- Cytochrome P-450 CYP2E1 Inhibitors [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 4-nitrophenol 2-monooxygenase (substance) [SNOMED CT concept]
- Cytochrome p450 CYP2E1 enzyme (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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