cytochrome p-450 cyp2b1

Preferred Label : cytochrome p-450 cyp2b1;

MeSH definition : A major cytochrome P-450 enzyme which is inducible by PHENOBARBITAL in both the LIVER and SMALL INTESTINE. It is active in the metabolism of compounds like pentoxyresorufin, TESTOSTERONE, and ANDROSTENEDIONE. This enzyme, encoded by CYP2B1 gene, also mediates the activation of CYCLOPHOSPHAMIDE and IFOSFAMIDE to MUTAGENS.;

MeSH synonym : benzyloxyresorufin o dealkylase; cyp 2b1; o-dealkylase, pentoxyresorufin; pentoxyresorufin o dealkylase; 7 benzyloxyresorufin o dealkylase; 7 pentylresorufin o depentylase; 7-benzyloxyresorufin o-dealkylase; 7-pentylresorufin o-depentylase; cytochrome p450 2b1; PROD; BROD; CYP2B1; benzyloxyresorufin O-Dealkylase; pentoxyresorufin O-Dealkylase; cytochrome P 450 CYP2B1;

Registry Number MeSH : EC 1.14.14.1;

MeSH annotation : do not confuse with other cytochrome P-450 CYP's;

Is substance : O;

UNII : EC 1.14.14.1;

Details

Origin ID

D019362;

UMLS CUI

C0070319;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Indexing information
- 7-ethynylcoumarin [MeSH Supplementary Concept]
Record concept(s)
- cytochrome P-450 CYP2B1 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cytochrome p450 CYP2B1 enzyme (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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