cytochrome p-450 cyp1a1

Preferred Label : cytochrome p-450 cyp1a1;

MeSH definition : A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.;

MeSH synonym : cyp 1a1; cyp1a1; cyp1a1 protein; erod; ethoxyresorufin dealkylase; ethylresorufin o-deethylase; 7-ethoxyresorufin o-deethylase; cytochrome p450 ia1; ethoxyresorufin O-Deethylase; cytochrome P 450 CYP1A1;

Registry Number MeSH : EC 1.14.14.1;

MeSH annotation : do not confuse with other cytochrome P-450 CYP's;

Is substance : O;

UNII : EC 1.14.14.1;

Details

Origin ID

D019363;

UMLS CUI

C0059735;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Aromatase [NCIt concept]
- CYP1A1 Gene [NCIt concept]
- Cytochrome P450 19A1 [NCIt concept]
- Cytochrome P450 1A1 [NCIt concept]
- Cytochrome P450 1A2 [NCIt concept]
- Cytochrome P450 2C18 [NCIt concept]
- Cytochrome P450 2C19 [NCIt concept]
- Cytochrome P450 2C8 [NCIt concept]
- Cytochrome P450 2C9 [NCIt concept]
- Cytochrome P450 2D6 [NCIt concept]
- Cytochrome P450 2E1 [NCIt concept]
- Cytochrome P450 3A4 [NCIt concept]
- Cytochrome P450 3A5 [NCIt concept]
- Cytochrome P450 3A7 [NCIt concept]
- Cytochrome p450, subfamily I, polypeptide 1 [OMIM gene]
- eroded [Radlex concept]
Currated CISMeF NLP mapping
- Cytochrome p450 CYP1A1 enzyme (substance) [SNOMED CT concept]
Indexing information
- rhapontigenin [MeSH Supplementary Concept]
Record concept(s)
- cytochrome P-450 CYP1A1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- CYP1A1 protein, human [MeSH Supplementary Concept]
- Cyp1a1 protein, mouse [MeSH Supplementary Concept]
- estrogen 2-hydroxylase [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Cytochrome p450 CYP19A1 enzyme (substance) [SNOMED CT concept]
- Cytochrome p450 CYP1A1 enzyme (substance) [SNOMED CT concept]

Keyword's position in hierarchy(ies) :

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