Pantoprazole - CISMeF

Preferred Label : Pantoprazole;

NCIt definition : A substituted benzimidazole and proton pump inhibitor with antacid activity. Pantoprazole is a lipophilic weak base that crosses the parietal cell membrane and enters the acidic parietal cell canaliculus where it becomes protonated, producing the active metabolite sulphenamide, which forms an irreversible covalent bond with two sites of the H /K -ATPase enzyme located on the gastric parietal cell, thereby inhibiting both basal and stimulated gastric acid production.;

UNII : D8TST4O562;

InChIKey : IQPSEEYGBUAQFF-UHFFFAOYSA-N;

CAS number : 102625-70-7; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 102625-70-7 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Chemical formula : C16H15F2N3O4S;

ChEBI ID : CHEBI:7915;

Codes from synonyms : 50757; 386;

Details

Origin ID

C29346;

UMLS CUI

C0081876;

Automatic exact mappings (from CISMeF team)
- Pantoprazole [ICD-11 Extension code]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Pantoprazole [MeSH Descriptor]
- Pantoprazole [LOINC component]
- Pantoprazole (substance) [SNOMED CT concept]
- Product containing pantoprazole (medicinal product) [SNOMED CT concept]
- pantoprazole [ATC Code]
- pantoprazole [MeSH concept]
Validated automatic mappings to BTNT
- pantoprazole [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2C19 [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
has_salt_form
- Pantoprazole Sodium [NCIt concept]
is_free_acid_or_base_form_of
- Pantoprazole Sodium [NCIt concept]

Keyword's position in hierarchy(ies) :

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