NCIt definition : The sodium salt form of a substituted benzimidazole with proton pump inhibitor activity.
Pantoprazole is a lipophilic, weak base that crosses the parietal cell membrane and
enters the acidic parietal cell canaliculus where it becomes protonated, producing
the active metabolite sulfenamide, which forms an irreversible covalent bond with
two sites of the H /K -ATPase enzyme located on the gastric parietal cell, thereby
inhibiting both basal and stimulated gastric acid production.;