Nilutamide - CISMeF

Preferred Label : Nilutamide;

NCIt synonyms : 5,5-Dimethyl-3-[4-nitro-3-(trifluoro-methyl)phenyl]-2,4-imidazolidinedione; 1-(3'-Trifluoromethyl-4'-nitrophenyl)-4,4-dimethylimidazoline-3,5-dione;

NCIt definition : A synthetic, nonsteroidal agent with antiandrogenic properties. Nilutamide preferentially binds to androgen receptors and blocks androgen receptor activation by testosterone and other androgens; this agent may inhibit androgen-dependent growth of normal and neoplastic prostate cells. (NCI04);

Alternative definition : NCI-GLOSS: A drug that blocks the effects of male hormones in the body. It is a type of antiandrogen.;

UNII : 51G6I8B902;

InChIKey : XWXYUMMDTVBTOU-UHFFFAOYSA-N;

CAS number : 63612-50-0;

Drug name : Anandron; Nilandron;

Molecule name : RU-23908;

Chemical formula : C12H10F3N3O4;

NSC code : 684588;

ChEBI ID : CHEBI:7573;

Codes from synonyms : CDR0000045300; 353;

Details

Origin ID

C1173;

UMLS CUI

C0068771;

See also inter- (CISMeF)
- Product containing nilutamide (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Nilutamide [ICD-11 Extension code]
- Nilutamide (substance) [SNOMED CT concept]
- Product containing nilutamide (medicinal product) [SNOMED CT concept]
- nilutamide [ATC Code]
- nilutamide [MeSH concept]
- nilutamide [SNOMED Notion]
- nilutamide [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- nilutamide [ATC Code]
chemical_or_drug_is_metabolized_by_enzyme
- Cytochrome P450 2C19 [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- HemOnc Agent Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]
- Operational Ontology for Radiation Oncology Prostate Cancer Terminology [NCIt concept]
has_target
- Androgen Receptor [NCIt concept]
is_component_of_chemotherapy_regimen
- Buserelin/Nilutamide [NCIt concept]
- Goserelin/Nilutamide [NCIt concept]
- Leuprolide/Nilutamide [NCIt concept]
- Nilutamide Regimen [NCIt concept]
- Nilutamide/Triptorelin [NCIt concept]

Keyword's position in hierarchy(ies) :

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