Sorbitol Dehydrogenase

Preferred Label : Sorbitol Dehydrogenase;

NCIt synonyms : SORD; EC 1.1.1.-; RDH; SDH; Microsomal Aldehyde Dehydrogenase; L-Iditol 2-Dehydrogenase; Polyol Dehydrogenase; XDH; (R,R)-Butanediol Dehydrogenase; Epididymis Secretory Sperm Binding Protein Li 95n; Ribitol Dehydrogenase; Xylitol Dehydrogenase;

NCIt definition : Sorbitol dehydrogenase (357 aa, 38 kDa) is encoded by the human SORD gene. This protein plays a role in the interconversion of glucose and fructose to sorbitol and the reversible conversion of sugar alcohols to ketoses.;

NCIt note : Sorbitol dehydrogenase has the following polyol dehydrogenase activities (R,R)-butanediol dehydrogenase (EC 1.1.1.4), L-iditol 2-dehydrogenase (EC 1.1.1.14), ribitol dehydrogenase (EC 1.1.1.56) and xylitol dehydrogenase (EC 1.1.1.9). (UniProt);

Details

Origin ID

C208012;

OMIM relation
- Sorbitol dehydrogenase [OMIM gene]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- SORD Gene [NCIt concept]
gene_product_expressed_in_tissue
- Epididymis [NCIt concept]
- Kidney [NCIt concept]
- Liver [NCIt concept]
- Prostate Gland [NCIt concept]
gene_product_has_associated_anatomy
- Cilium [NCIt concept]
- Cytosol [NCIt concept]
- Exosome [NCIt concept]
- Extracellular Space [NCIt concept]
- Mitochondrial Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Metal Binding Site [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Fructose and Mannose Metabolism Pathway [NCIt concept]
- Pentose and Glucuronate Interconversions Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Biosynthetic Process [NCIt concept]
- Carbohydrate Metabolic Process [NCIt concept]
- Catabolic Process [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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