NADPH Oxidase 4

Preferred Label : NADPH Oxidase 4;

NCIt synonyms : Kidney Oxidase-1; EC 1.6.3.-; Renal NAD(P)H-Oxidase; Kidney Superoxide-Producing NADPH Oxidase; NOX4;

NCIt definition : NADPH oxidase 4 (578 aa, 67 kDa) is encoded by the human NOX4 gene. This protein plays a role as an oxygen sensor in cell differentiation and signal transduction.;

Details

Origin ID

C104572;

UMLS CUI

C1454287;

OMIM relation
- Nadph oxidase 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NADPH Oxidase 4 [MeSH Descriptor]
- NOX4 protein, human [MeSH concept]
- NOX4 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- NOX4 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
gene_product_is_physical_part_of
- NADPH Oxidase Complex [NCIt concept]
gene_product_plays_role_in_biological_process
- Free Radical Formation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Regulatory Process [NCIt concept]
- Signal Transduction [NCIt concept]
is_target
- Imipramine Blue [NCIt concept]
- Setanaxib [NCIt concept]

Keyword's position in hierarchy(ies) :

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