24-Hydroxycholesterol 7-Alpha-Hydroxylase

Preferred Label : 24-Hydroxycholesterol 7-Alpha-Hydroxylase;

NCIt synonyms : Oxysterol 7-Alpha-Hydroxylase; Cytochrome P450, Subfamily XXXIX Polypeptide 1; EC 1.14.13.99; Cytochrome P450 39A1; hCYP39A1; CYP39A1;

NCIt definition : 24-hydroxycholesterol 7-alpha-hydroxylase (469 aa, 54 kDa) is encoded by the human CYP39A1 gene. This protein is involved in the conversion of cholesterol to bile acids.;

Details

Origin ID

C114646;

UMLS CUI

C1432901;

Automatic exact mappings (from CISMeF team)
- 24-hydroxycholesterol 7alpha-hydroxylase activity [GO term]
- Cytochrome p450, family 39, subfamily a, polypeptide 1 [OMIM gene]
- oxysterol 7-alpha-hydroxylase [MeSH concept]
- oxysterol 7-alpha-hydroxylase [MeSH Supplementary Concept]
OMIM relation
- Cytochrome p450, family 39, subfamily a, polypeptide 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CYP39A1 protein, human [MeSH Supplementary Concept]
- CYP39A1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CYP39A1 Gene [NCIt concept]
- Cytochrome P450 Family Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_chemical_classification
- Heme Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Bile Acid Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Detoxification [NCIt concept]
- Digestion [NCIt concept]
- Hydroxylation [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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