Preferred Label : oxysterol 7-alpha-hydroxylase;
MeSH note : a widely distributed P-450 enzyme found in brain, testis, ovary, prostate, liver,
colon, kidney, and small intestine; catalyzes 7-alpha-hydroxylation of a broad spectrum
of substrates including dehydroepiandrosterone, pregnenolone, 25- or 27-hydroxycholesterol;
is important in bile acid synthesis; mutation of CYP7B1 gene causes severe neonatal
giant cell HEPATITIS;
MeSH synonym : DHEA 7-alpha-hydroxylase; 25-hydroxycholesterol 7alpha-hydroxylase; 3 beta-hydroxysteroid 7-alpha-hydroxylase; 25-hydroxycholesterol 7-alpha-hydroxylase; 3 beta-hydroxysteroid-7 alpha-hydroxylase; 5 alpha-androstane 3 beta,17 beta-diol 7 alpha-hydroxylase; 5alpha-androstane-3beta,17beta-diol 7-alpha-hydroxylase; dehydroepiandrosterone 7-alpha-hydroxylase; 25-HC 7alpha-hydroxylase; oxysterol 7 alpha-hydroxylase;
MeSH Related Number : dehydroepiandrosterone 7-hydroxylase; EC 1.14.-; 2E7DZF35YK;
Registry Number MeSH : EC 1.14.13.-;
Related CAS MeSH : EC 1.14.-; EC 1.14.- (dehydroepiandrosterone 7-hydroxylase);
related registry number list (CISMeF) : EC 1.14.-;
Is substance : O;
Origin ID : C115867;
UMLS CUI : C0760412;
MeSH term(s) associated for indexing
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