Hypoxanthine-Guanine Phosphoribosyltransferase

Preferred Label : Hypoxanthine-Guanine Phosphoribosyltransferase;

NCIt synonyms : HGPRT; HGPRTase; Hypoxanthine Phosphoribosyltransferase-1; HPRT1; Hypoxanthine Phosphoribosyltransferase 1; EC 2.4.2.8;

NCIt definition : Hypoxanthine-guanine phosphoribosyltransferase (218 aa, 25 kDa) is encoded by the human HPRT1 gene. This protein plays a role in nucleoside metabolism.;

NCIt note : Protein_Plays_Role_In_Biological_Process: Purine Salvage;

NCI Metathesaurus CUI : CL322751;

Details

Origin ID

C38496;

UMLS CUI

C5441712;

OMIM relation
- Hypoxanthine guanine phosphoribosyltransferase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Hypoxanthine phosphoribosyltransferase [LOINC component]
- Hypoxanthine phosphoribosyltransferase (substance) [SNOMED CT concept]
- hypoxanthine phosphoribosyltransferase [MeSH Descriptor]
- hypoxanthine phosphoribosyltransferase [MeSH concept]
- hypoxanthine phosphoribosyltransferase [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- HPRT1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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