E3 Ubiquitin-Protein Ligase COP1

Preferred Label : E3 Ubiquitin-Protein Ligase COP1;

NCIt synonyms : EC 6.3.2.-, Formerly; RING Finger Protein 200; Constitutive Photomorphogenesis Protein 1 Homolog; hCOP1; Ring Finger and WD Repeat Domain 2; RING Finger and WD Repeat Domain Protein 2; RING Finger and WD Repeat Domains-Containing Protein 2; Putative Ubiquitin Ligase COP1; E3 Ubiquitin-Protein Ligase RFWD2; RING-Type E3 Ubiquitin Transferase RFWD2; EC 2.3.2.27; COP1;

NCIt definition : E3 ubiquitin-protein ligase COP1 (731 aa, 80 kDa) is encoded by the human COP1 gene. This protein is involved in post-translational ubiquitination of target proteins.;

Details

Origin ID

C119606;

UMLS CUI

C1174826;

Automatic exact mappings (from CISMeF team)
- Caspase recruitment domain-containing protein 16 [OMIM gene]
- Ring finger and wd repeat domains-containing protein 2 [OMIM gene]
- coat protein complex i [MeSH Descriptor]
OMIM relation
- Ring finger and wd repeat domains-containing protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- COP1 protein, human [MeSH Supplementary Concept]
- COP1 protein, human [MeSH concept]
gene_encodes_gene_product
- COP1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- WD Repeat [NCIt concept]
gene_product_is_element_in_pathway
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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