Trifunctional Enzyme Subunit Beta, Mitochondrial

Preferred Label : Trifunctional Enzyme Subunit Beta, Mitochondrial;

NCIt synonyms : Beta-Ketothiolase; Hydroxyacyl-CoA Dehydrogenase Trifunctional Multienzyme Complex Subunit Beta; 3-Ketoacyl-CoA Thiolase; EC 2.3.1.16; EC 2.3.1.155; Acetyl-CoA Acyltransferase; TP-Beta; HADHB;

NCIt definition : Trifunctional enzyme subunit beta, mitochondrial (474 aa, 51 kDa) is encoded by the human HADHB gene. This protein plays a role in breaking down fatty acids to produce acetyl-Coenzyme A.;

NCIt note : The mitochondrial trifunctional enzyme is a heterotetramer composed of 2 alpha (HADHA) and 2 beta (HADHB) subunits.;

Details

Origin ID

C201718;

OMIM relation
- Hydroxyacyl-coa dehydrogenase/3-ketoacyl-coa thiolase/enoyl-coa hydratase, beta subunit [OMIM gene]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- HADHB Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
- Mitochondrial Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Fatty Acid Biosynthesis Pathway [NCIt concept]
- Fatty Acid Elongation Pathway in Mitochondria [NCIt concept]
- Fatty Acid Metabolism Pathway [NCIt concept]
- Valine, Leucine and Isoleucine Degradation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Catabolic Process [NCIt concept]
- Fatty Acid Metabolism [NCIt concept]

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