PR Domain Zinc Finger Protein 8

Preferred Label : PR Domain Zinc Finger Protein 8;

NCIt synonyms : PRDM8; PR Domain-Containing Protein 8; EC 2.1.1.-; PR-Domain Containing Protein 8; PR Domain Containing 8;

NCIt definition : PR domain zinc finger protein 8 (689 aa, 72 kDa) is encoded by the human PRDM8 gene. This protein is involved in histone methylation and transcriptional repression of steroidogenesis marker genes and genes involved in neural development and neuronal differentiation.;

Details

Origin ID

C212166;

OMIM relation
- Pr domain-containing protein 8 [OMIM gene]
concept_is_in_subset
- Pediatric Oncology Biomarkers/Targets Associated with Other Relevant Evidence [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- PRDM8 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- C2H2 Zinc Finger [NCIt concept]
- SET Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Cell Survival [NCIt concept]
- DNA Binding [NCIt concept]
- Histone Methylation [NCIt concept]
- Methylation [NCIt concept]
- Neural Development [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Transcriptional Repression [NCIt concept]

Keyword's position in hierarchy(ies) :

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