Matrilysin - CISMeF

Preferred Label : Matrilysin;

NCIt synonyms : EC 3.4.24.23; Pump-1 Protease; MMP-7; Matrin; Matrix Metalloproteinase-7; Matrix Metalloprotease-7; Matrix Metalloproteinase 7; Matrix Metalloprotease 7; Uterine Metalloproteinase; MMP7;

NCIt definition : Matrilysin (267 aa, 30 kDa) is encoded by the human MMP7 gene. This protein plays a role in the mediation of extracellular matrix protein degradation.;

Details

Origin ID

C98113;

UMLS CUI

C1429447;

Automatic exact mappings (from CISMeF team)
- Matrilysin (substance) [SNOMED CT concept]
- Matrix metalloproteinase 7 [OMIM gene]
- matrine [MeSH concept]
- matrix metallopeptidase 7 [HGNC gene]
- matrix metalloproteinase 7 [MeSH Descriptor]
- matrix metalloproteinase 7 [MeSH concept]
False automatic mappings
- Matrines [MeSH Descriptor]
OMIM relation
- Matrix metalloproteinase 7 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MMP7 protein, human [MeSH Supplementary Concept]
- MMP7 protein, human [MeSH concept]
- Matrilysin (substance) [SNOMED CT concept]
- matrix metalloproteinase 7 [MeSH Descriptor]
- matrix metalloproteinase 7 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- MMP7 Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Endopeptidase [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_is_element_in_pathway
- Adherens Junction Stabilization Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Syndecan-1-Mediated Signaling Pathway [NCIt concept]
- Wnt Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Extracellular Matrix Degradation [NCIt concept]
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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