Alpha-Mannosidase 2

Preferred Label : Alpha-Mannosidase 2;

NCIt synonyms : Mannosidase Alpha Class 2A Member 1; Mannosyl-Oligosaccharide 1,3-1,6-Alpha-Mannosidase; EC 3.2.1.114; Man II; AMan II; Golgi Integral Membrane Protein 7; MAN2A1; Golgi Alpha-Mannosidase II;

NCIt definition : Alpha-mannosidase 2 (1144 aa, 131 kDa) is encoded by the human MAN2A1 gene. This protein plays a role in the final hydrolytic step in the N-glycan maturation pathway.;

NCI Metathesaurus CUI : CL1927058;

Details

Origin ID

C204084;

UMLS CUI

C5891047;

OMIM relation
- Mannosidase, alpha, class 2a, member 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- MAN2A1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Golgi Apparatus [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- N-Glycan Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Biosynthetic Process [NCIt concept]
- Carbohydrate Metabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Glycosylation [NCIt concept]
is_target
- Tridolgosir [NCIt concept]
- Tridolgosir Hydrochloride [NCIt concept]

Keyword's position in hierarchy(ies) :

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