Serine Hydroxymethyltransferase, Cytosolic

Preferred Label : Serine Hydroxymethyltransferase, Cytosolic;

NCIt synonyms : Glycine Hydroxymethyltransferase; Serine Methylase; SHMT1; SHMT; EC 2.1.2.1;

NCIt definition : Serine hydroxymethyltransferase, cytosolic (483 aa, 53 kDa) is encoded by the human SHMT1 gene. This protein is involved in the conversion of glycine to serine.;

Details

Origin ID

C104970;

UMLS CUI

C3538858;

Automatic exact mappings (from CISMeF team)
- Glycine hydroxymethyltransferase (substance) [SNOMED CT concept]
- Serine hydroxymethyltransferase, cytosolic [OMIM gene]
- glycine hydroxymethyltransferase [MeSH Descriptor]
- glycine hydroxymethyltransferase [MeSH concept]
- glycine hydroxymethyltransferase [SNOMED Notion]
OMIM relation
- Serine hydroxymethyltransferase, cytosolic [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- SHMT1 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cyanoamino Acid Metabolism Pathway [NCIt concept]
- Glycine, Serine and Threonine Metabolism Pathway [NCIt concept]
- Glyoxylate and Dicarboxylate Metabolism Pathway [NCIt concept]
- One Carbon Pool by Folate Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Amino Acid Biosynthesis [NCIt concept]
- Folic Acid Metabolic Process [NCIt concept]
- Methylation [NCIt concept]
- Nucleotide Biosynthesis Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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