Sialidase-1 - CISMeF

Preferred Label : Sialidase-1;

NCIt synonyms : Acetylneuraminyl Hydrolase; NEU1; EC 3.2.1.18; G9 Sialidase; Lysosomal Sialidase; N-Acetyl-Alpha-Neuraminidase 1;

NCIt definition : Sialidase-1 (415 aa, 45 kDa) is encoded by the human NEU1 gene. This protein plays a role in the removal of terminal sialic acid residues from glycoproteins and glycolipids.;

NCIt note : Sialidase-1 is part of a heterotrimeric complex that includes beta-galactosidase and lysosomal protective protein (cathepsin A).;

Détails

Origin ID

C203911;

UMLS CUI

C1436326;

OMIM relation
- Neuraminidase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NEU1 protein, human [MeSH Supplementary Concept]
- NEU1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- NEU1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Exosome [NCIt concept]
- Extracellular Space [NCIt concept]
- Lysosome [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Glycoprotein Degradation Pathway [NCIt concept]
- Lysosome Assembly Pathway [NCIt concept]
- Sphingolipid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Catabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Lipid Metabolic Process [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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