E3 Ubiquitin-Protein Ligase RAD18

Preferred Label : E3 Ubiquitin-Protein Ligase RAD18;

NCIt synonyms : EC 6.3.2.-, Formerly; hRAD18; hHR18; RAD18; Postreplication Repair Protein RAD18; RING Finger Protein 73; EC 2.3.2.27;

NCIt definition : E3 ubiquitin-protein ligase RAD18 (495 aa, 56 kDa) is encoded by the human RAD18 gene. This protein plays a role in both ubiquitination and postreplication repair of UV-damaged DNA.;

Details

Origin ID

C106246;

UMLS CUI

C1434353;

Automatic exact mappings (from CISMeF team)
- Rad18 e3 ubiquitin protein ligase [OMIM gene]
OMIM relation
- Rad18 e3 ubiquitin protein ligase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RAD18 protein, human [MeSH Supplementary Concept]
- RAD18 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- RAD18 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Binding [NCIt concept]
- DNA Repair [NCIt concept]
- Monoubiquitination [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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