Histone Acetylase

Preferred Label : Histone Acetylase;

NCIt synonyms : Histone Acetyltransferase; EC 2.3.1.48; HAT;

NCIt definition : Class of enzymes that catalyze the acetylation of specific lysine residues of histones, proteins that organize eukaryotic DNA into chromatin. Among the proteins that exhibit histone acetyltransferase activity are various transcription factor coactivators. E.C. 2.3.1.48.;

Details

Origin ID

C17302;

UMLS CUI

C0062773;

Biochemical function of gene products
- Cyclic AMP-Dependent Transcription Factor ATF-2 [NCIt concept]
- Nuclear Receptor Coactivator 1 [NCIt concept]
- Nuclear Receptor Coactivator 3 [NCIt concept]
- SAGA [NCIt concept]
- Transcription Initiation Factor TFIID Subunit 1 [NCIt concept]
Currated CISMeF NLP mapping
- histone acetyltransferase [SNOMED Notion]
False automatic mappings
- Histone acetyltransferase (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Histone acetyltransferase (substance) [SNOMED CT concept]
- histone acetyltransferase [SNOMED Notion]
- histone acetyltransferases [MeSH concept]
- histone acetyltransferases [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Histone Acetylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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