Nuclear Receptor Coactivator 1

Preferred Label : Nuclear Receptor Coactivator 1;

NCIt synonyms : Steroid Receptor Coactivator 1; SRC-1; F-SRC-1; Renal Carcinoma Antigen NY-REN-52; bHLHe74; Protein Hin-2; RIP160; Class E Basic Helix-Loop-Helix Protein 74; SRC1; EC 2.3.1.48; NCOA1; NCoA-1; Nuclear Receptor Coactivator-1;

NCIt definition : Nuclear receptor coactivator 1 (1441 aa, 157 kDa) is encoded by the human NCOA1 gene. This protein is involved in the modulation of hormone-dependent transcription.;

Details

Origin ID

C17977;

UMLS CUI

C1743596;

OMIM relation
- Nuclear receptor coactivator 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- NCOA1 protein, human [MeSH concept]
- NCOA1 protein, human [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- NCOA1 protein, human [MeSH concept]
- NCOA1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- NCOA1 Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Histone Acetylase [NCIt concept]
- Transcription Coactivator [NCIt concept]
gene_product_has_structural_domain_or_motif
- bHLH Domain [NCIt concept]
gene_product_is_element_in_pathway
- Androgen Receptor Regulation Pathway [NCIt concept]
- Chromatin Remodeling Complex and Coactivator Pathway [NCIt concept]
- Gene Expression Regulation by Vitamin D Receptor Pathway [NCIt concept]
- Glucocorticoid Receptor Regulatory Network [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Obesity and Thermogenesis Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- RXR and RAR Heterodimerization with Other Nuclear Receptor Signaling Pathway [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
- Retinoic Acid Receptor Family-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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