" /> DNA (Cytosine-5)-Methyltransferase 3B - CISMeF





Preferred Label : DNA (Cytosine-5)-Methyltransferase 3B;

NCIt synonyms : DNA (Cytosine-5-)-Methyltransferase 3B; EC 2.1.1.37; M.HsaIIIB; DNA Methyltransferase HsaIIIB; ICF; DNA (Cytosine-5-)-Methyltransferase 3 Beta; DNMT3B Protein; DNA MTase HsaIIIB; DNMT3B; DNA Methyltransferase 3B; DNA Methyltransferase-3B;

NCIt definition : DNA (cytosine-5)-methyltransferase 3B (853 aa, 96 kDa) is encoded by the human DNMT3B gene. This protein is involved in DNA methylation.;

NCIt note : DNA (cytosine-5)-methyltransferase 3B is expressed as six isoforms (1, 2, 3, 4, 5 and 6) that are produced by alternative splicing. Isoforms 4 and 5 are probably not functional due to the deletion of two conserved methyltransferase motifs. Isoform 1 is expressed in all tissues except brain, skeletal muscle and PBMC, 3 is ubiquitous, 4 is expressed in all tissues except brain, skeletal muscle, lung and prostate and 5 is detectable only in testis and at very low level in brain and prostate. (UniProt);

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29/07/2025


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