Methionine Synthase Reductase

Preferred Label : Methionine Synthase Reductase;

NCIt synonyms : EC 1.16.1.8; MSR; MTRR; 5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase;

NCIt definition : Methionine synthase reductase (725 aa, 80 kDa) is encoded by the human MTRR gene. This protein plays a role in both methionine biosynthesis and B vitamin metabolism.;

Details

Origin ID

C105128;

UMLS CUI

C1453956;

Automatic exact mappings (from CISMeF team)
- 5-methyltetrahydrofolate-homocysteine methyltransferase reductase [ORDO Gene]
- 5-methyltetrahydrofolate-homocysteine methyltransferase reductase [HGNC gene]
- Methionine synthase reductase [OMIM gene]
- Methionine synthase-cobalamin methyltransferase (cob(II)alamin reducing) (substance) [SNOMED CT concept]
- [methionine synthase] reductase activity [GO term]
- methionine synthase reductase [MeSH concept]
- methionine synthase reductase [MeSH Supplementary Concept]
OMIM relation
- Methionine synthase reductase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MTRR protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- MTRR Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Amino Acid Biosynthesis [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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