Glutathione Peroxidase 3

Preferred Label : Glutathione Peroxidase 3;

NCIt synonyms : EC 1.11.1.9; GPx-P; GPx-3; Plasma Glutathione Peroxidase; GSHPx-P; GSHPx-3; Extracellular Glutathione Peroxidase; GPX3;

NCIt definition : Glutathione peroxidase 3 (226 aa, 26 kDa) is encoded by the human GPX3 gene. This protein is involved in hydrogen peroxide and lipid peroxide detoxification.;

NCIt note : Glutathione peroxidase 3 contains a selenocysteine (Sec) residue at its active site.;

Details

Origin ID

C127004;

UMLS CUI

C1436542;

Automatic exact mappings (from CISMeF team)
- Glutathione peroxidase 3 [OMIM gene]
- glutathione peroxidase 3 [HGNC gene]
OMIM relation
- Glutathione peroxidase 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GPX3 protein, human [MeSH Supplementary Concept]
- GPX3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GPX3 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Plasma [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arachidonic Acid Metabolism Pathway [NCIt concept]
- Glutathione Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cellular Stress Response [NCIt concept]
- Detoxification [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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