N-Acetylgalactosamine-6-Sulfatase

Preferred Label : N-Acetylgalactosamine-6-Sulfatase;

NCIt synonyms : Galactosamine-6-Sulfatase; GALNS; Galactose-6-Sulfate Sulfatase; Chondroitinsulfatase; GalN6S; N-Acetylgalactosamine-Sulfate Sulfatase; GalNAc6S Sulfatase; EC 3.1.6.4; N-Acetylgalactosamine-6-Sulfate Sulfatase; Galactosamine-6-Sulfate Sulfatase; Chondroitinase;

NCIt definition : N-acetylgalactosamine-6-sulfatase (522 aa, 58 kDa) is encoded by the human GALNS gene. This protein plays a role in hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.;

Details

Origin ID

C201864;

OMIM relation
- Galactosamine-6-sulfate sulfatase [OMIM gene]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- GALNS Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Lysosome [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Glycosaminoglycan Degradation Pathway [NCIt concept]
- Lysosome Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Catabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]

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