Metallopeptidase

Preferred Label : Metallopeptidase;

NCIt synonyms : METALLOPROTEASE; Metalloproteinase;

NCIt definition : A proteolytic enzyme that uses a metal ion, usually zinc, to catalyze the hydrolysis of peptide bonds. This protease is inhibited by metal chelating agents.;

Details

Origin ID

C16843;

UMLS CUI

C0025543;

Biochemical function of gene products
- ADAM Family Protein [NCIt concept]
- Leukotriene A-4 Hydrolase [NCIt concept]
- Peptidase Family M12B [NCIt concept]
Currated CISMeF NLP mapping
- Metalloproteinase (substance) [SNOMED CT concept]
- metalloproteases [MeSH Descriptor]
- metalloproteases [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Metalloproteinase (substance) [SNOMED CT concept]
- metalloproteases [MeSH Descriptor]
- metalloproteases [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]
is_chemical_classification_of_gene_product
- Probable Carboxypeptidase X1 [NCIt concept]

Keyword's position in hierarchy(ies) :

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