Leukotriene A-4 Hydrolase

Preferred Label : Leukotriene A-4 Hydrolase;

NCIt synonyms : LTA-4 Hydrolase; EC 3.3.2.6; Leukotriene A(4) Hydrolase; LTA4H;

NCIt definition : Leukotriene A-4 hydrolase (611 aa, 69 kDa) is encoded by the human LTA4H gene. This protein plays a role in the conversion of leukotriene A4 to leukotriene B4.;

Details

Origin ID

C116951;

UMLS CUI

C3889162;

Automatic exact mappings (from CISMeF team)
- Leukotriene a4 hydrolase [OMIM gene]
- Leukotriene-A4 hydrolase (substance) [SNOMED CT concept]
- leukotriene A4 hydrolase [HGNC gene]
- leukotriene A4 hydrolase [MeSH concept]
- leukotriene A4 hydrolase [MeSH Supplementary Concept]
- leukotriene-A4 hydrolase activity [GO term]
OMIM relation
- Leukotriene a4 hydrolase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- LTA4H Gene [NCIt concept]
gene_product_has_biochemical_function
- Metallopeptidase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arachidonic Acid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Eicosanoid Modulation [NCIt concept]
- Hydrolysis [NCIt concept]
- Peptide Metabolism [NCIt concept]
is_target
- Tosedostat [NCIt concept]

Keyword's position in hierarchy(ies) :

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