Eicosanoid Modulation

Preferred Label : Eicosanoid Modulation;

NCIt definition : Eicosanoid Modulation involves a change in the quality of the existing state of activity of hormone-like endogenous unsaturated and oxygenated fatty acid derivatives of arachidonic acid (eicosanoids) that act near the site of synthesis and have a specific regulatory effect on the activity of target cells in host defense reactions, immediate hypersensitivity, and inflammation. Eicosanoids include prostaglandins, leukotrienes, thromboxanes, and hydroxyeicosatetraenoic acid compounds.;

Details

Origin ID

C40647;

UMLS CUI

C1512178;

Semantic type(s)
- Physiologic Function [UMLS semantic type]
biological_process_involves_gene_product
- 12-(S)-Hydroxy-5,8,10,14-Eicosatetraenoic Acid Receptor [NCIt concept]
- 15-Hydroxyprostaglandin Dehydrogenase [NAD+] [NCIt concept]
- Aldo-Keto Reductase Family 1 Member C3 [NCIt concept]
- Carbonyl Reductase [NADPH] 1 [NCIt concept]
- Leukotriene A-4 Hydrolase [NCIt concept]
process_involves_gene
- AKR1C3 Gene [NCIt concept]
- AKR1C3 wt Allele [NCIt concept]
- CBR1 Gene [NCIt concept]
- CBR1 wt Allele [NCIt concept]
- GPR31 Gene [NCIt concept]
- GPR31 wt Allele [NCIt concept]
- HPGD Gene [NCIt concept]
- HPGD wt Allele [NCIt concept]
- LTA4H Gene [NCIt concept]
- LTA4H wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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