Preferred Label : GPR31 wt Allele;
NCIt synonyms : 12-(S)-HETE Acid Receptor Gene; HETER1; Hydroxyeicosatetraenoic (HETE) Acid Receptor 1 Gene; G-Protein Coupled Receptor 31 Gene; 12-HETER; 12-(S)-Hydroxy-5,8,10,14-Eicosatetraenoic Acid (HETE) Receptor Gene; BA517H2.2 (G Protein-Coupled Receptor 31) Gene; G Protein-Coupled Receptor 31 wt Allele; HETER;
NCIt definition : Human GPR31 wild-type allele is located in the vicinity of 6q27 and is approximately
3 kb in length. This allele, which encodes 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic
acid receptor protein, plays a role in lipid-dependent G protein-coupled receptor
signaling. This gene plays a role in membrane localization of an alternatively spliced
variant of KRAS, KRAS4B, which is associated with proliferation, survival and macropinocytosis
of tumor cells in KRAS-dependent cancers.;
NCI Metathesaurus CUI : CL1779264;
GenBank Accession Number : U65402;
PubMed : 28619714;
Origin ID : C187023;
UMLS CUI : C5575579;
Automatic exact mappings (from CISMeF team)
- OMIM relation
- Semantic type(s)
- concept_is_in_subset
- gene_found_in_organism
- gene_in_chromosomal_location
- gene_plays_role_in_process
