AKR1C3 wt Allele

Preferred Label : AKR1C3 wt Allele;

NCIt synonyms : HSD17B5; DD3; hluPGFS; HA1753; PGFS; HAKRe; DDX; Aldo-Keto Reductase Family 1, Member C3 Gene; Aldo-Keto Reductase Family 1 Member C3 wt Allele; HAKRB; HAKRD; Aldo-Keto Reductase Family 1, Member C3 (3-Alpha Hydroxysteroid Dehydrogenase, Type II) Gene; KIAA0119; DDH2;

NCIt definition : Human AKR1C3 wild-type allele is located within 10p15-p14 and is approximately 72 kb in length. This allele, which encodes aldo-keto reductase family 1 member C3 protein, plays a role in the metabolism of prostaglandins and steroids.;

NCIt note : Expression is analyzed as part of the 17-gene leukemia stem cell scoring system (LSC17). (Nature. 2016; doi:10.1038/nature20598.);

NCI Metathesaurus CUI : CL512261;

GenBank Accession Number : L43839;

Details

Origin ID

C129053;

UMLS CUI

C4284023;

Automatic exact mappings (from CISMeF team)
- Aldo-keto reductase family 1, member c2 [OMIM gene]
- Aldo-keto reductase family 1, member c3 [OMIM gene]
- Prostate cancer antigen 3 [OMIM gene]
- aldo-keto reductase family 1 member C2 [ORDO Gene]
- dichlorodiphenyl dichloroethylene [MeSH Descriptor]
OMIM relation
- Aldo-keto reductase family 1, member c3 [OMIM gene]
See also inter- (CISMeF)
- Developmental dysplasia of the hip 2 [OMIM Phenotype]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 10p15-p14 [NCIt concept]
gene_is_element_in_pathway
- Arachidonic Acid Metabolism Pathway [NCIt concept]
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_plays_role_in_process
- Eicosanoid Modulation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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