Prostaglandin Reductase 1

Preferred Label : Prostaglandin Reductase 1;

NCIt synonyms : Dithiolethione-Inducible Gene 1 Protein; D3T-Inducible Gene 1 Protein; EC 1.3.1.74; NADP-Dependent Leukotriene B4 12-Hydroxydehydrogenase; DIG-1; 15-Oxoprostaglandin 13-Reductase; Leukotriene B4 12-Hydroxydehydrogenase; EC 1.3.1.48; NAD(P)H-Dependent Alkenal/One Oxidoreductase; PTGR1; PRG-1;

NCIt definition : Prostaglandin reductase 1 (329 aa, 36 kDa) is encoded by the human PTGR1 gene. This protein plays a role in the metabolism of eicosanoids, including the reduction of leukotriene B4 to 12-oxo-leukotriene B4.;

Details

Origin ID

C203766;

UMLS CUI

C1433492;

OMIM relation
- Prostaglandin reductase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- LTB4DH protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- PTGR1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Exosome [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Arachidonic Acid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Eicosanoid Modulation [NCIt concept]
- Fatty Acid Metabolism [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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