NCIt synonyms : Hydroxyprostaglandin Dehydrogenase 15-(NAD) wt Allele; PGDH1; 15-PGDH; PGDH; 15-Hydroxyprostaglandin Dehydrogenase, Type I Gene; PHOAR1; Short Chain Dehydrogenase/Reductase Family 36C, Member 1 Gene; SDR36C1;
NCIt definition : Human HPGD wild-type allele is located within 4q34-q35 and is approximately 32 kb
in length. This allele, which encodes 15-hydroxyprostaglandin dehydrogenase [NAD ]
protein, plays a role in the regulation of prostaglandin metabolism. Mutation of the
gene is associated with primary hypertrophic osteoathropathy autosomal recessive and
cranioosteoarthropathy.;