Sterol 26-Hydroxylase, Mitochondrial

Preferred Label : Sterol 26-Hydroxylase, Mitochondrial;

NCIt synonyms : Cholestanetriol 26-Monooxygenase; EC 1.14.13.15; 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-Hydroxylase; Vitamin D(3) 25-Hydroxylase; Cytochrome P450 27A1; Cytochrome P-450C27/25; Sterol 27-hydroxylase; Cytochrome P450 27; CYP27A1;

NCIt definition : Sterol 26-hydroxylase, mitochondrial (531 aa, 60 kDa) is encoded by the human CYP27A1 gene. This protein is involved in cholesterol homeostasis and bile synthesis.;

Details

Origin ID

C104151;

UMLS CUI

C3538880;

OMIM relation
- Cytochrome p450, subfamily xxviia, polypeptide 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CYP27A1 Gene [NCIt concept]
- Cytochrome P450 Family Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_chemical_classification
- Heme Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Detoxification [NCIt concept]
- Hydroxylation [NCIt concept]
- Intermediary Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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