E3 Ubiquitin-Protein Ligase NEDD4

Preferred Label : E3 Ubiquitin-Protein Ligase NEDD4;

NCIt synonyms : E3 Ubiquitin-protein Ligase NEDD4 Protein; NEDD-4; Cell Proliferation-Inducing Gene 53 Protein; Receptor-Potentiating Factor 1; EC 6.3.2.-, Formerly; Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 4; EC 2.3.2.26;

NCIt definition : E3 ubiquitin-protein ligase NEDD4 (1000 aa, 115 kDa) is encoded by the human NEDD4 gene. This protein is involved in the transfer of ubiquitin to target proteins and may play a role in virion budding from infected cells and tumor suppression.;

Details

Origin ID

C68584;

UMLS CUI

C2348357;

Automatic exact mappings (from CISMeF team)
- NEDD4 E3 ubiquitin protein ligase [HGNC gene]
- Neural precursor cell expressed, developmentally downregulated 4 [OMIM gene]
OMIM relation
- Neural precursor cell expressed, developmentally downregulated 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- NEDD4 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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