Alpha-Ketoglutarate-Dependent Dioxygenase FTO

Preferred Label : Alpha-Ketoglutarate-Dependent Dioxygenase FTO;

NCIt synonyms : Protein Fto; Fat Mass and Obesity-Associated Protein; EC 1.14.11.-; AlkB Homolog 9; FTO;

NCIt definition : Alpha-ketoglutarate-dependent dioxygenase FTO (505 aa, 58 kDa) is encoded by the human FTO gene. This protein is involved in the demethylation of RNA and DNA.;

Details

Origin ID

C99470;

UMLS CUI

C2351322;

Automatic exact mappings (from CISMeF team)
- Alpha-Ketoglutarate-Dependent Dioxygenase FTO [MeSH Descriptor]
- Alpha-Ketoglutarate-Dependent Dioxygenase FTO [MeSH concept]
- FTO alpha-ketoglutarate dependent dioxygenase [ORDO Gene]
- FTO alpha-ketoglutarate dependent dioxygenase [HGNC gene]
- Fto alpha-ketoglutarate-dependent dioxygenase [OMIM gene]
OMIM relation
- Fto alpha-ketoglutarate-dependent dioxygenase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- FTO protein, human [MeSH concept]
- FTO protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- FTO Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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