ATP-Citrate Synthase

Preferred Label : ATP-Citrate Synthase;

NCIt synonyms : ATP Citrate Lyase; Citrate Cleavage Enzyme; ATP-Citrate (Pro-S-)-Lyase; EC 2.3.3.8; ACLY;

NCIt definition : ATP-citrate synthase (1101 aa, 121 kDa) is encoded by the human ACLY gene. This protein is involved in both the synthesis of cytosolic acetyl-CoA and the de novo lipid synthesis.;

Details

Origin ID

C107109;

UMLS CUI

C3815504;

Automatic exact mappings (from CISMeF team)
- Atp citrate lyase [OMIM gene]
Currated CISMeF NLP mapping
- ATP citrate (pro-S)-Lyase [MeSH Descriptor]
- ATP citrate (pro-S)-Lyase [MeSH concept]
- Adenosine triphosphate citrate (pro-3S)-lyase (substance) [SNOMED CT concept]
- atp citrate (pro-3s)-lyase [SNOMED Notion]
OMIM relation
- Atp citrate lyase [OMIM gene]
See also inter- (CISMeF)
- ATP citrate lyase [HGNC gene]
- Atp citrate lyase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ACLY Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]

Keyword's position in hierarchy(ies) :

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