Preferred Label : ATP citrate (pro-S)-Lyase;
MeSH definition : An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate
to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents
an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC
4.1.3.8.;
MeSH synonym : atp dependent citrate lyase; citrate lyase, atp; citrate synthase, atp; cleavage enzyme, citrate; lyase, atp-dependent citrate; citrate lyase, atp-dependent; atp citrate (pro-3s)-lyase; atp citrate lyase; lyase, atp citrate; citrate cleavage enzyme; atp citrate synthase; synthase, atp citrate; atp-dependent citrate lyase;
MeSH CAS label : ATP:citrate oxaloacetate-lyase ((pro-S)-CH2COO(-)--acetyl-CoA) (ATP-dephosphorylating);
MeSH Related Number : 9027-95-6 (CAS RN);
Registry Number MeSH : EC 2.3.3.8;
Is substance : O;
UNII : EC 2.3.3.8;
Origin ID : D001275;
UMLS CUI : C0004199;
Allowable qualifiers
- Automatic exact mappings (from CISMeF team)
- Currated CISMeF NLP mapping
- Indexing information
- Record concept(s)
- Related MeSH Supplementary Concept(s)
- Semantic type(s)
- UMLS correspondences (same concept)
An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate
to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents
an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC
4.1.3.8.
