ATP citrate (pro-S)-Lyase

Preferred Label : ATP citrate (pro-S)-Lyase;

MeSH definition : An enzyme that, in the presence of ATP and COENZYME A, catalyzes the cleavage of citrate to yield acetyl CoA, oxaloacetate, ADP, and ORTHOPHOSPHATE. This reaction represents an important step in fatty acid biosynthesis. This enzyme was formerly listed as EC 4.1.3.8.;

MeSH synonym : atp dependent citrate lyase; citrate lyase, atp; citrate synthase, atp; cleavage enzyme, citrate; lyase, atp-dependent citrate; citrate lyase, atp-dependent; atp citrate (pro-3s)-lyase; atp citrate lyase; lyase, atp citrate; citrate cleavage enzyme; atp citrate synthase; synthase, atp citrate; atp-dependent citrate lyase;

MeSH CAS label : ATP:citrate oxaloacetate-lyase ((pro-S)-CH2COO(-)--acetyl-CoA) (ATP-dephosphorylating);

MeSH Related Number : 9027-95-6 (CAS RN);

Registry Number MeSH : EC 2.3.3.8;

Is substance : O;

UNII : EC 2.3.3.8;

Détails

Origin ID

D001275;

UMLS CUI

C0004199;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- ACLY Gene [NCIt concept]
- ATP citrate lyase [HGNC gene]
- Atp citrate lyase [OMIM gene]
Currated CISMeF NLP mapping
- ATP-Citrate Synthase [NCIt concept]
- Adenosine triphosphate citrate (pro-3S)-lyase (substance) [SNOMED CT concept]
- atp citrate (pro-3s)-lyase [SNOMED Notion]
Indexing information
- 2,2-difluorocitric acid [MeSH Supplementary Concept]
- 3-(carboxymethyl)-5-(6-(2,4-dichlorophenyl)hexyl)-3-hydroxytetrahydrofuran-2-one [MeSH Supplementary Concept]
- 3-carboxy-11-(2,4-dichlorophenyl)-3,5-dihydroxyundecanoic acid [MeSH Supplementary Concept]
- SB 201076 [MeSH Supplementary Concept]
Record concept(s)
- ATP citrate (pro-S)-Lyase [MeSH concept]
Related MeSH Supplementary Concept(s)
- ACLA protein, arabidopsis [MeSH Supplementary Concept]
- ACLB protein, arabidopsis [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Adenosine triphosphate citrate (pro-3S)-lyase (substance) [SNOMED CT concept]
- atp citrate (pro-3s)-lyase [SNOMED Notion]

Position du mot-clé dans l'(les) arborescence(s) :

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