E3 Ubiquitin-Protein Ligase HERC2

Preferred Label : E3 Ubiquitin-Protein Ligase HERC2;

NCIt synonyms : HECT Domain and RCC1-Like Domain-Containing Protein 2; EC 6.3.2.-, Formerly; EC 2.3.2.26;

NCIt definition : E3 ubiquitin-protein ligase HERC2 (4834 aa, 527 kDa) is encoded by the human HERC2 gene. This protein is involved in ubiquitin-dependent retention of DNA repair proteins.;

Details

Origin ID

C117251;

UMLS CUI

C1439265;

OMIM relation
- Hect domain and rcc1-like domain 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- HERC2 protein, human [MeSH Supplementary Concept]
- HERC2 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- HERC2 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Centriole [NCIt concept]
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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