GTPase Nras - CISMeF

Preferred Label : GTPase Nras;

NCIt synonyms : Transforming Protein p21 N-Ras; N-Ras Protein; NRAS; Transforming Protein N-Ras; p21 N-Ras Protein;

NCIt definition : GTPase NRas (189 aa, 21 kDa) is encoded by the human NRAS gene. This protein is involved in the mediation of GTPase-dependent signaling.;

Details

Origin ID

C17384;

UMLS CUI

C3657629;

Automatic exact mappings (from CISMeF team)
- NRAS proto-oncogene, GTPase [ORDO Gene]
- Nras protooncogene, gtpase [OMIM gene]
- Proto-Oncogene proteins p21(ras) [MeSH Descriptor]
OMIM relation
- Nras protooncogene, gtpase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NRAS protein, human [MeSH Supplementary Concept]
- NRAS protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- NRAS Gene [NCIt concept]
- RAS Family Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_gene_product_variant
- NRAS NP_002515.1:p.G12A [NCIt concept]
- NRAS NP_002515.1:p.G12C [NCIt concept]
- NRAS NP_002515.1:p.G12D [NCIt concept]
- NRAS NP_002515.1:p.G12R [NCIt concept]
- NRAS NP_002515.1:p.G12S [NCIt concept]
- NRAS NP_002515.1:p.G12V [NCIt concept]
- NRAS NP_002515.1:p.G12X [NCIt concept]
- NRAS NP_002515.1:p.G13D [NCIt concept]
- NRAS NP_002515.1:p.G13R [NCIt concept]
- NRAS NP_002515.1:p.G13S [NCIt concept]
- NRAS NP_002515.1:p.G13V [NCIt concept]
- NRAS NP_002515.1:p.G13X [NCIt concept]
- NRAS NP_002515.1:p.Q61E [NCIt concept]
- NRAS NP_002515.1:p.Q61H [NCIt concept]
- NRAS NP_002515.1:p.Q61K [NCIt concept]
- NRAS NP_002515.1:p.Q61L [NCIt concept]
- NRAS NP_002515.1:p.Q61P [NCIt concept]
- NRAS NP_002515.1:p.Q61R [NCIt concept]
- NRAS NP_002515.1:p.Q61X [NCIt concept]
- NRAS Protein Variant [NCIt concept]
gene_product_has_structural_domain_or_motif
- GTP Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Acute Myeloid Leukemia Pathway [NCIt concept]
- Apoptosis Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- B Cell Receptor Signaling Pathway [NCIt concept]
- Bladder Cancer Pathway [NCIt concept]
- Chemokine Signaling Pathway [NCIt concept]
- Chronic Myeloid Leukemia Pathway [NCIt concept]
- ERBB Family Signaling Pathway [NCIt concept]
- Endocytosis Pathway [NCIt concept]
- Endometrial Cancer Pathway [NCIt concept]
- Fc Epsilon Receptor I Signaling Pathway KEGG [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Gap Junction Assembly Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Long-Term Depression Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- MAPK Signaling Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- Melanoma Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Non-Small Cell Lung Cancer Pathway [NCIt concept]
- Papillary Thyroid Carcinoma Pathway [NCIt concept]
- Prostate Cancer Pathway [NCIt concept]
- Renal Cell Carcinoma Pathway [NCIt concept]
- T Cell Receptor Signaling Pathway KEGG [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- mTOR Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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