E3 Ubiquitin Ligase TRAF3IP2

Preferred Label : E3 Ubiquitin Ligase TRAF3IP2;

NCIt synonyms : NFkB-Activating Protein ACT1; Nuclear Factor Kappa-B Activator 1; TRAF3 Interacting Protein 2; E3 Ubiquitin-Protein Ligase CIKS; EC 2.3.2.27; TRAF3IP2; Adapter Protein CIKS; Connection to IKK and SAPK/JNK; TRAF3-Interacting Protein 2; Nuclear Factor NF-Kappa-B Activator 1; Connection to I-Kappa-B Kinase and Stress-Activated Protein Kinase;

NCIt definition : E3 ubiquitin ligase TRAF3IP2 (574 aa, 65 kDa) is encoded by the human TRAF3IP2 gene. This protein is involved in the regulation of signal transduction downstream of tumor necrosis factor receptors and polyubiquitination of target proteins.;

Details

Origin ID

C178602;

UMLS CUI

C0961208;

Automatic exact mappings (from CISMeF team)
- TRAF3 interacting protein 2 [HGNC gene]
- TRAF3 interacting protein 2 [ORDO Gene]
- Traf3-interacting protein 2 [OMIM gene]
OMIM relation
- Traf3-interacting protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TRAF3IP2 protein, human [MeSH Supplementary Concept]
- TRAF3IP2 protein, human [MeSH concept]
gene_encodes_gene_product
- Adaptor Signaling Protein Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
- TRAF3IP2 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Interleukin Signaling Process [NCIt concept]
- Polyubiquitination [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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