DNA dC to dU-Editing Enzyme APOBEC-3G

Preferred Label : DNA dC to dU-Editing Enzyme APOBEC-3G;

NCIt synonyms : APOBEC-Related Cytidine Deaminase; CEM-15; CEM15; ARP-9; APOBEC-Related Protein 9; ARCD; DNA dC- dU-Editing Enzyme APOBEC-3G; Deoxycytidine Deaminase; A3G; Phorbolin-Like Protein MDS019; APOBEC-3G Protein; APOBEC3G;

NCIt definition : DNA dC- dU-editing enzyme APOBEC-3G protein (384 aa, 46 kDa) is encoded by the human APOBEC3G gene. This protein is a member of the cytidine deaminase gene family and may play a role in editing mRNA, cellular growth and cell cycle control. The enzyme inhibits the viral replication of several virion species; however, the lethality of human T-cell leukemia virus type I may exhibit resistance to the activity of this enzyme.;

Details

Origin ID

C68591;

UMLS CUI

C1143167;

OMIM relation
- Apolipoprotein b mrna-editing enzyme, catalytic polypeptide-like 3g [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- APOBEC3G protein, human [MeSH concept]
- APOBEC3G protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- APOBEC3G Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_biochemical_function
- Cytidine Deaminase [NCIt concept]
gene_product_has_chemical_classification
- APOBEC Family Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- HIV-1 Infection Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antiviral Response [NCIt concept]
- Hydrolysis [NCIt concept]
- Immunity [NCIt concept]

Keyword's position in hierarchy(ies) :

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