Peroxiredoxin-4

Preferred Label : Peroxiredoxin-4;

NCIt synonyms : Thioredoxin Peroxidase AO372; Antioxidant Enzyme 372; EC 1.11.1.15; Peroxiredoxin IV; Antioxidant Enzyme AOE372; Epididymis Secretory Sperm Binding Protein Li 97n; AOE37-2; Prx-IV; Thioredoxin-Dependent Peroxide Reductase A0372; PRDX4;

NCIt definition : Peroxiredoxin-4 (271 aa, 31 kDa) is encoded by the human PRDX4 gene. This protein plays a role in both redox regulation and nuclear factor NF-kappa-B activation in cells.;

Details

Origin ID

C116657;

UMLS CUI

C0633225;

Automatic exact mappings (from CISMeF team)
- Peroxiredoxin 4 [OMIM gene]
- peroxiredoxin IV [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PRDX4 protein, human [MeSH Supplementary Concept]
- PRDX4 protein, human [MeSH concept]
Validated automatic mappings to NTBT
- peroxiredoxins [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- PRDX4 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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